Perninae is a subfamily of medium-sized broad-winged birds of prey. These are birds of warmer climates, although the Pernis species (European honey buzzard and crested honey buzzard) have a more extensive range.

Several of the species in this group eat mainly insects, and the honey-buzzards are specialist feeders on wasp larvae. Reptiles are also taken by several birds in this group.

Several authorities consider Gypaetinae to be within or even synonymous with Perninae.