Mesobatrachia is a suborder of frogs in the order Anura. Recognized as a group in 1993, the name (meso- "middle" batrachia "frogs") is contrasted with the primitive Archaeobatrachia and the more diverse and advanced Neobatrachia.

The Mesobatrachia comprise five fossorial families, including the spadefoot toads of Europe, North America, and East Asia, the parsley frogs, and the Mexican burrowing toad (Rhinophrynus dorsalis), as well as one obligatorily aquatic family, the Pipidae of Africa and South America.

Mesobatrachia are a relatively new group, only having been identified as such in 1993.