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Hyalinobatrachium is a genus of glass frogs characterized by having a bulbous liver covered by white pigment, a transparent parietal peritoneum, extensive membrane between the outer fingers, and lacking a humeral spine in adult males.

The genus is currently defined to include Hyalinobatrachium fleischmanni and its closest relatives. Some species (the former Hyalinobatrachium antisthenesi and Hyalinobatrachium pulveratum) were excluded from Hyalinobatrachium due to its closer relationships with the genus Cochranella. On the other hand, some species currently placed in Hyalinobatrachium were formerly placed in the genus Centrolenella (now a synonym of Centrolene)

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